Transitional mutations increase to mitigate the bias effect on the X chromosome inactivation that leads to the onset of mutations with pathological effects in the gene for iduronato2 sulphatase (IDS) (3.1.6.13). Revista de Investigaciones Universidad del Quindío, [S. l.], v. 26, n. 1, p. 135–138, 2017. DOI: 10.33975/riuq.vol26n1.139. Disponível em: https://revistas.uniquindio.edu.co/ojs/index.php/riuq/article/view/139. Acesso em: 25 jun. 2026.